<p> Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (<db_xref db="EC" dbkey="2.7.1.11"/>) in which two tandem copies of the phosphofructokinase are found [<cite idref="PUB00013526"/>]. Members are found, often including several isozymes, in animals and fungi and in the bacterium <taxon tax_id="267747">Propionibacterium acnes KPA171202</taxon> (a human skin commensal).</p><p>Phosphofructokinase (PFK) catalyses the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate, which then enters the Embden-Meyerhof pathway. PFK is a key regulatory enzyme in glycolysis.</p><p>For additional information please see [<cite idref="PUB00013527"/>, <cite idref="PUB00013528"/>, <cite idref="PUB00013529"/>].</p> 6-phosphofructokinase, eukaryotic type